publications

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PubMed

Enhancer RNAs are an important regulatory layer of the epigenome

RNAs Interact with BRD4 to Promote Enhanced Chromatin Engagement and Transcription Activation. 

Rahnamoun H, Lee J, Sun Z, Lu H, Ramsey KM, Komives EA, and Lauberth SM. 

Nature Structural and Molecular Biology

2018, August 3, 2018, 25(8):687-697. PubMed PMID: 30076409. 

https://www.nature.com/articles/s41594-018-0102-0.

Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4.

Homa Rahnamoun, Juyeong Hong, Zhengxi Sun, Jihoon Lee, Hanbin Lu, and Shannon M.Lauberth. JBC 2018 June 28,

Journal of Biological Chemistry 

PubMed PMID:29954944. 

https://www.jbc.org/content/early/2018/06/28/jbc.RA118.003387

Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling.

Homa Rahnamoun, Hanbin Lu, Sascha H. Duttke, Christopher K. Glass, Christopher Benner, and Shannon M. Lauberth. Nature Communications

2017 September 29, 8(1):754. PubMed PMID: 28963538; PubMed Central PMCID: PMC5622043https://www.nature.com/articles/s41467-017-01117-y

The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output.

Stijf-Bultsma Y., Sommer L., Tauber M., Baalbaki M., Giardoglou P., Jones DR., Gelato KA., Van  Pelt J., Shah Z., Rahnamoun H., Toma C., Anderson KE., Hawkins P., Lauberth SM., Haramis AG., Hart D., Fischle W., and Divecha N.  Molecular Cell

doi:10.1016/j.molcel.2015.03.009

https://www.sciencedirect.com/science/article/pii/S1097276515001744

H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation.

Lauberth SM., Nakayama T., Wu X., Ferris A., Tang, Z., Hughes S.H., and Roeder, R.G. (2013). 

Cell

2013. 1021-1036.

https://pubmed.ncbi.nlm.nih.gov/23452851/